Gelatinous marrow transformation

Gelatinous marrow transformation, also know as serous atrophy of the marrow, refers to a marrow disorder that occurs with chronic illness and poor nutritional status.  It is characterized by atrophy of the fatty marrow and loss of hematopoietic cells, replaced by extracellular gelatinous substances. On MR imaging this is seen as fluid intensity regions in the marrow that are initially patchy but that become confluent. These progress in the same order as red to yellow marrow conversion (distal to proximal).

This may be seen with:

  • cachexia
  • anorexia nervosa or other eating disorders
  • AIDS
  • alcoholism
  • acute febrile illness
  • malignancies
  • congestive heart failure
  • myelodysplastic syndrome

 

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Article Information

rID: 1377
Tag: aids
Synonyms or Alternate Spellings:

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