Gestational and secretory hyperplasia

Gestational and secretory hyperplasia are pregnancy and lactation related physiological changes occurring in breast tissues.

The normal physiology of pregnancy causes a lobular enlargement of terminal duct lobular units along with formation of new ones during the second month of gestation. In the following 2 months, there is vacuolation and accumulation of secretions seen in these distended lobular glands.

  • areas of increased breast parenchymal density
  • increased breast size
  • focally or diffusely distributed round microcalcifications (hyperplasia in the lobular acini)
  • rarely irregular, linearly distributed or branching microcalcifications (ductal hyperplasia) - raises suspicion of malignancy

Pregnancy-like hyperplasia or pseudolactational hyperplasia, which manifests with the same radiologic and pathologic findings in non-pregnant, non-lactating women.

No described malignant potentiality yet.

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Article information

rID: 25964
System: Breast
Tags: breast, refs
Synonyms or Alternate Spellings:
  • Pregnancy related hyperplasia of breast

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