Gestational and secretory hyperplasia
Citation, DOI & article data
Gestational and secretory hyperplasia are pregnancy and lactation related physiological changes occurring in breast tissues.
The normal physiology of pregnancy causes a lobular enlargement of terminal duct lobular units along with formation of new ones during the second month of gestation. In the following 2 months, there is vacuolation and accumulation of secretions seen in these distended lobular glands.
- areas of increased breast parenchymal density
- increased breast size
- focally or diffusely distributed round microcalcifications (hyperplasia in the lobular acini)
- rarely irregular, linearly distributed or branching microcalcifications (ductal hyperplasia) - raises suspicion of malignancy
No described malignant potentiality yet.
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- 2. Mercado CL, Koenigsberg TC, Hamele-Bena D et-al. Calcifications associated with lactational changes of the breast: mammographic findings with histologic correlation. AJR Am J Roentgenol. 2002;179 (3): 685-9. doi:10.2214/ajr.179.3.1790685 - Pubmed citation