Citation, DOI, disclosures and article data
At the time the article was created Frank Gaillard had no recorded disclosures.View Frank Gaillard's current disclosures
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Glial cells, or neuroglia, are cells that surround the neurons of the central nervous system embedded between them, providing both structural and physiological support 1-3. Together they account for almost half of the total mass 1 and 90% of all cells of the central nervous system 3. These numbers are now contentious as a novel cell counting technique known as 'isotopic fractionation' has shown that the ratio between glial cells and neurons is actually one-to-one 4.
Glial cells are broadly divided into macroglia and microglia. Each cell type has specific distribution and function.
History and etymology
The term glia is from the Ancient Greek for "glue", as initially these cells were thought to merely act as supporting structures for neurons.
- 1. Barbara Young, Phillip Woodford, Geraldine O'Dowd. Wheater's Functional Histology. 6th EditionISBN: 9780702054884
- 2. Richard S. Snell. Clinical Neuroanatomy. ISBN: 9780781794275
- 3. Richard A. Prayson. Neuropathology. ISBN: 9781437709490
- 4. Verkhratsky A, Nedergaard M. Physiology of Astroglia. (2018) Physiological reviews. 98 (1): 239-389. doi:10.1152/physrev.00042.2016 - Pubmed