Glial fibrillary acid protein (GFAP)
Last revised by Francesco Buemi ◉
on 25 Jan 2022
Citation, DOI, disclosures and article data
Citation:
Gaillard F, Buemi F, Sharma R, Glial fibrillary acid protein (GFAP). Reference article, Radiopaedia.org (Accessed on 18 Jan 2025) https://doi.org/10.53347/rID-51742
Permalink:
rID:
51742
Article created:
Disclosures:
At the time the article was created Frank Gaillard had no recorded disclosures.
View Frank Gaillard's current disclosures
Last revised:
25 Jan 2022,
Francesco Buemi ◉
Disclosures:
At the time the article was last revised Francesco Buemi had no recorded disclosures.
View Francesco Buemi's current disclosures
Revisions:
4 times, by
3 contributors -
see full revision history and disclosures
Systems:
Sections:
Synonyms:
- GFAP
- Glial fibrillary acid protein
Glial fibrillary acid protein (GFAP) is a commonly used target for immunohistochemistry and is positive in many glial cells and tumors of glial origin. GFAP is the building block for intermediate filaments which are abundant in the cytoplasms particularly of astrocytes.
Related pathology
Quiz questions
{"containerId":"expandableQuestionsContainer","displayRelatedArticles":true,"displayNextQuestion":true,"displaySkipQuestion":true,"articleId":51742,"questionManager":null,"mcqUrl":"https://radiopaedia.org/articles/glial-fibrillary-acid-protein-gfap/questions/565?lang=us"}
References
- 1. Barbara Young, James S. Lowe, Alan Stevens, John W. Heath, Philip J. Deakin. Wheater's Functional Histology. ISBN: 9781437700756
Incoming Links
Articles:
- Alexander disease
- CNS neuroblastoma, FOXR2-activated
- Gliosarcoma
- Adenocarcinoma of the lacrimal glands
- Chordoid glioma
- Gangliocytoma
- Diffuse glioneuronal tumour with oligodendroglioma like features and nuclear clusters
- Ependymal cyst
- Astrocytes
- Pilocytic astrocytoma
- Primary meningeal malignant melanoma
- Astrocytoma, IDH-mutant
- Cauda equina neuroendocrine tumour
- Paraganglioma
- Rosette-forming glioneuronal tumour
- Diffuse midline glioma, H3 K27-altered
- Calcifying pseudoneoplasm of the neuraxis
- Diffuse hemispheric glioma H3 G34 mutant
- Papillary tumour of the pineal region
- Cortical tubers
Cases:
Multiple choice questions:
Related articles: Histology
- cells (general)
- general cellular structure
- cell membrane
- nucleus
- nucleolus
- chromatin
- cytoplasm
- organelles
- cytoskeleton
- endoplasmic reticulum
- smooth
- rough
- Golgi complex
- lysosomes
- mitochondria
- peroxisomes
- ribosomes
- body systems
-
blood
- platelets
- red blood cells
- white blood cells
- granular
- non-granular
- central nervous system
-
blood
- general cellular structure
- immunohistochemistry
-
histological stains
- alcian blue stain
- azan stain
- Giemsa stain
- Gram stain
- hematoxylin and eosin stain (H&E)
- immunoperoxidase staining
- Luxol fast blue stain
- Masson's trichrome stain
- methylene blue
- Nissl stain
- oil red O stain
- osmium stain
- Papanicolaou stain
- periodic acid-Schiff reaction (PAS)
- Prussian blue stain
- reticulin stain
- silver stain
- Sudan stains
- toluidine blue stain
- van Gieson stain
- Ziehl-Neelsen stain
- specific features and structures