Gracile bones refer to changes in the skeleton in which the bones are more slender than usual (over-tubulated) and occasionally deformed in other ways such as being abnormally curved. This may occur in a number of disorders and can occur with or without fractures.
- neurofibromatosis type 1 2
- immobilization/paralysis: often gracile bone matches area of paralysis
- muscular dystrophy
- muscular atrophy
- rheumatoid arthritis (juvenile)
- osteogenesis imperfecta
- dysplasias (gracile bone dysplasias)
- hemophilia: will typically have gracile diaphyses with expanded epiphyses 3
The useful mnemonic for learning the causes of gracile bones is NIMROD.
- 1. Kozlowski K, Masel J, Sillence DO et-al. Gracile bone dysplasias. Pediatr Radiol. 2002;32 (9): 629-34. doi:10.1007/s00247-002-0719-2 - Pubmed citation
- 2. Schindeler A, Little DG. Recent insights into bone development, homeostasis, and repair in type 1 neurofibromatosis (NF1). Bone. 2008;42 (4): 616-22. doi:10.1016/j.bone.2007.11.006 - Pubmed citation
- 3. Helms CA. Fundamentals of skeletal radiology. Saunders. ISBN:1455751545. Read it at Google Books - Find it at Amazon
- 4. Larson CM, Henderson RC. Bone mineral density and fractures in boys with Duchenne muscular dystrophy. Journal of pediatric orthopedics. 20 (1): 71-4. Pubmed