Granulomatosis with polyangiitis (renal manifestations)

Dr Henry Knipe et al.

The renal manifestations of granulomatosis with polyangiitis (GPA) are occult on imaging, especially when compared to the pulmonary changes. Approximately half of GPA patients have kidney disease at presentation.

Clinical presentation

Reduced renal function, proteinuria and haematuria. 


GPA affects the kidneys with the development of necrotising glomerulonephritis in ~60% (range 39-80%) of patients. 

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Article Information

rID: 38241
System: Urogenital
Section: Pathology
Tag: cases
Synonyms or Alternate Spellings:
  • Renal manifestations of granulomatosis with polyangiitis (GPA)
  • Wegener granulomatosis (renal manifestations)
  • Wegener's granulomatosis (renal manifestations)

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