Granulomatosis with polyangiitis (renal manifestations)
The renal manifestations of granulomatosis with polyangiitis (GPA) are occult on imaging, especially when compared to the pulmonary changes. Approximately half of GPA patients have kidney disease at presentation.
Reduced renal function, proteinuria and haematuria.
GPA affects the kidneys with the development of necrotising glomerulonephritis in ~60% (range 39-80%) of patients.
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