Granulomatous prostatitis

Granulomatous prostatitis is a nodular form of chronic prostatitis. It is usually diagnised by biopsy.

  • idiopathic
  • infection
  • iatrogenic: (BCG,post radiation)
  • systemic disease such as
    • sarcoidosis 
    • autoimmune diseases

One form of classificiations is as

Another form is as

  • non specific granulomatous prostatitis
  • tubercular granulomatous prostatitis
  • postsurgical granulomatous prostatitis
  • allergic granulomatous prostatitis
  • xanthogranulomatous prostatitis

The histological form can vary dependant on the subtype 7

Often there is no definite ultrasound or MRI finding that allows a specific diagnosis of granulomatous prostatitis to be made, or differentiation from prostatic carcinoma 2.

Widening of the prostatic urethra however may be a useful feature in differentiation from prostatic carcinoma 1.

May be seen as a hypoechoic nodule (~70%) or diffuse hypoechoic peripheral zone (~30%)

Three morphological MRI patterns have been described which are diffuse, nodular (tumour like), and cystic with mural nodule 3.

Signal characteristics include 

  • T2: affected regions hypointense
  • C+ (Gd): no enhancement following Gd-DTPA

It first described by F H Tanner and J R McDonald in 1943 13

Prostate pathology
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Article information

rID: 24640
System: Urogenital
Section: Pathology
Tags: refs, cases
Synonyms or Alternate Spellings:

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