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The term grouped calcifications is used in mammography when relatively few breast microcalcifications reside within a small area. There must be at least five calcifications present within 1 cm of each other 3. At the most, it may refer to a larger number of calcifications present within 2 cm of each other 3.
An outdated synonym is calcific cluster or clustered calcification. The term 'grouped' is preferred in the latest BI-RADS manual 3.
Homogeneous, smooth clustered microcalcifications can be due to 1:
- fibrocystic disease (often scattered clusters throughout all quadrants bilaterally)
- lobular carcinoma in situ (LCIS)
- invasive lobular carcinoma
Pleomorphic clustered microcalcifications can be due to:
- 1. Ellen Shaw De Paredes. Atlas of Mammography. (2007) ISBN: 9780781764339 - Google Books
- 2. Kerridge W, Kryvenko O, Thompson A, Shah B. Fat Necrosis of the Breast: A Pictorial Review of the Mammographic, Ultrasound, CT, and MRI Findings with Histopathologic Correlation. Radiol Res Pract. 2015;2015:613139. doi:10.1155/2015/613139 [Pubmed]
- 3. Acr. 2013 ACR BI-RADS Atlas. (2014) ISBN: 9781559030168 - Google Books