Hematopoietic stem cell transplantation

Last revised by Daniel J Bell ◉ on 3 Feb 2020

Citation, DOI, disclosures and article data

Citation:

Knipe H, Bell D, St-Amant M, Hematopoietic stem cell transplantation. Reference article, Radiopaedia.org (Accessed on 03 Dec 2024) https://doi.org/10.53347/rID-43034

DOI:

https://doi.org/10.53347/rID-43034

Permalink:

https://radiopaedia.org/articles/43034

rID:

43034

Article created:

19 Feb 2016, Henry Knipe ◉

Disclosures:

At the time the article was created Henry Knipe had no recorded disclosures.

View Henry Knipe's current disclosures

Last revised:

3 Feb 2020, Daniel J Bell ◉

Disclosures:

At the time the article was last revised Daniel J Bell had no recorded disclosures.

View Daniel J Bell's current disclosures

Revisions:

5 times, by 3 contributors - see full revision history and disclosures

Systems:

Haematology, Oncology

Synonyms:

Hematopoietic stem cell transplantation (HSCT)
Bone marrow transplantation
Bone marrow transplant (BMT)
BMT

Hematopoietic stem cell transplantation (HSCT) (encompasses bone marrow transplantation (BMT)) is a relatively common procedure used to treat a wide spectrum of conditions ^1,2:

lymphoproliferative disorders, e.g. multiple myeloma (most common indication), lymphoma,
leukemia
solid tumors, e.g. neuroblastoma, Ewing sarcoma, extragonadal germ cell tumors
non-malignant disorders, e.g. bone marrow failure syndrome, severe aplastic anemia

There are a number of different types of HSCT ³:

autologous HSCT: the patient is the donor and recipient of hematopoietic stem cells
allogeneic HSCT: the patient is the recipient of hematopoietic stem cells sourced from another individual
- risk of developing graft versus host disease