Haematuria (adult)

Haematuria occurs when blood enters the urinary collecting system. There are many aetiologies for haematuria, and they range from benign and transient to gravely concerning. It can derive from the kidneys, ureters, bladder, prostate (in men), or urethra. Imaging can often be useful to determine the source of haematuria.

Haematuria can be considered in two main forms:

  • "gross" haematuria
  • microscopic haematuria

Pathology

Gross haematuria

Gross haematuria is considered >1 ml of blood in the urine. Red-colored urine (more red than brown) or clots in the urine is suggestive of a lower urinary tract source.

Microscopic haematuria

Microscopic haematuria may be either symptomatic or asymptomatic, and is defined as ≥3 red blood cells per hpf on 2 out of 3 urinalysis specimens 2.

Treatment and prognosis

Gross hematuria is almost always evaluated clinically, with cystoscopy, and with imaging (e.g. CT urogram).

Imaging workup for microscopic haematuria is controversial. Some societies advocate that in the absence of a known benign aetiology (such as vigorous exercise, infection, or menstruation), then a CT urogram is warranted 3,4. If the patient has known renal disease then an ultrasound of the kidneys and bladder may be more appropriate.

Some feel that the imaging workup in the setting of of microscopic haematuria has a high negative rate for malignancy, and suggest that instead of imaging all patients with microscopic haematuria, imaging should be reserved for higher-risk subsets 5.

Microsopic haematuria in children has a different treatment algorithm.

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Article Information

rID: 39589
System: Urogenital
Section: Pathology
Synonyms or Alternate Spellings:
  • Hematuria
  • Hematuria (adult)
  • Blood in urine

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