General isotropic DWI signal characteristics of hemorrhage on MRI may be recalled by the mnemonic:
- Hobbits Love Little Hairy Ladies
Mnemonic
-
Hobbits
- high isotropic DWI signal with reduced ADC values
- intracellular oxyhemoglobin: hyperacute (<1day)
-
Love
- low isotropic DWI signal with reduced ADC values
- intracellular deoxyhemoglobin: acute (1 to 3 days)
-
Little
- low isotropic DWI signal with reduced ADC values
- intracellular methemoglobin: early subacute (3 to 7 days)
-
Hairy
- high isotropic DWI signal with reduced ADC values
- extracellular methemoglobin: late subacute (7 to 14-28 days)
-
Ladies
- low isotropic DWI signal with increased ADC values (centrally)
- extracellular haemichromes at the central portion of the infarct: chronic (>14-28 days)
See hemorrhage on MRI article for more information.