The Haggitt level is a histopathological term used for describing the degree of infiltration from a malignant polypoidal lesion.
Levels of invasion
- 0: carcinoma in situ or intramucosal carcinoma
- 1: invasion of the submucosa, but limited to the head of the polyp
- 2: invasion extending into the neck of the polyp
- 3: invasion into any part of the stalk
- 4: invasion beyond the stalk into the submucosa of the bowel wall below the stalk but above the muscularis propria
History and etymology
Rodger C. Haggitt et al. studied 129 colorectal carcinomas that arose in adenomas and in which invasion was no deeper than submucosa of underlying colonic wall. Various factors were studied which included location, gross appearance, histological type of adenoma, grade of carcinoma, level of invasion, vascular invasion and adequacy of incisional margins.
- Kikuchi level (sessile tumour invasion classification)
- 1. http://www.virtualpathology.leeds.ac.uk/nbcs/guidelines.php
- 2. Haggitt RC, Glotzbach RE, Soffer EE, Wruble LD. Prognostic factors in colorectal carcinomas arising in adenomas: implications for lesions removed by endoscopic polypectomy. (1985) Gastroenterology. 89 (2): 328-36. Pubmed