Hepatic adrenal rest tumor

Last revised by Dr Jeremy Jones on 20 Sep 2021

Hepatic adrenal rest tumors (HART), previously been termed primary hypernephroma of the liver or hypernephroid carcinoma of the liver, are very rare liver tumors with histology similar to adrenocortical carcinoma

It tends to occur in younger patients and there is no recognized gender predilection.

It is considered to be derived from the adrenal rest in the liver. The presence of fat within the tumor is the most characteristic feature.

While imaging features are non-specific it usually appears as a round, well-defined mass in the liver. There may be a right lobe predilection. Lesions are typically subcapsular and can demonstrate hypervascularity. They often contain foci of calcification.

One specific radiographic feature is the presence of fat within the tumor.

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