Hepatic attenuation on CT
Hepatic attenuation on CT, reflected by Hounsfield values, depends on a combination of factors including the presence or absence, as well as the phase, of IV contrast administration.
Allowing for all these factors, the mean unenhanced attenuation value is around 55 HU 4.
Several intrinsic liver pathologies can cause a diffuse change in liver attenuation with increased hepatic fat being the most prevalent.
Diffusely increased attenuation
- iron deposition
- copper deposition
- glycogen storage diseases
- amiodarone hepatotoxicity: long-term amiodarone administration 7,8
- gold therapy 6
- previous Thorotrast administration