Hepatic inflammatory pseudotumour

Dr Henry Knipe and Dr Yuranga Weerakkody et al.

Hepatic inflammatory pseudotumours (IPT) are rare benign hepatic lesions.

Most common in young adults with males affected more than females 7

Aetiology is unknown 7

Macroscopic appearance

Hepatic IPT is often seen as a well-circumscribed, encapsulated inflammatory mass. 

Histology

Hepatic IPT characterised by a large population of polyclonal plasma cells with a variable amount of fibrosis, foamy histiocytes, and other chronic inflammatory cells 2.

Associations
Subtypes

Radiological findings are not characteristic and definitive diagnosis requires needle biopsy (sometimes insufficient 7) or surgery 3.

CT

In most reported cases, the they appear as hypo-attenuating masses with a variable degree of hepatic enhancement 2

MRI
Signal characteristics
  • T1: hypointense
  • T2: hyperintense
  • T1C+: heterogeneous enhancement 7
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Article information

rID: 17297
Section: Pathology
Tag: cases
Synonyms or Alternate Spellings:
  • Inflammatory pseudotumour of the liver
  • Hepatic inflammatory pseudotumours
  • Hepatic inflammatory pseudotumor
  • Hepatic inflammatory pseudotumors
  • Fibrous xanthoma of the liver
  • Xanthogranuloma of the liver
  • Plasma cell granuloma of liver

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