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Hepatic lymphoma

Hepatic lymphoma is a term given to any form of hepatic involvement with lymphoma. This can be broadly divided into:


Risk factors for developing hepatic lymphoma:

  • HIV/AIDS (25-46%)
  • hepatitis C (HCV) mostly in patients with non-Hodgkin’s lymphoma (15%)
  • organ transplantation (2-12%)
  • immunosuppression 

Radiographic features

Many tend to present as focal liver lesions 2. It may be difficult to differentiate primary vs. secondary from analysis of the liver lesion alone (at the time of initial writing).


Lesions are reported to be hypoattenuating on CT 4.


Reported signal characteristics include 1,2:

  • T1: hypointense (mild to moderate) relative to liver
  • T2: hyperintense relative to liver
  • C+ (Gd): transient increased perilesional enhancement is common

Article information

rID: 17148
Synonyms or Alternate Spellings:
  • Hepatic invovement with lymphoma
  • Lymphoma with hepatic involvement
  • Lymphoma with liver involevment

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Cases and figures

  • Case 1: hepatic involvement with NHL
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  • Case 2: hepatic involvement with NHL
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  • Case 3: NHL
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