Citation, DOI & article data
Hepatic steatosis, also known as hepatosteatosis, refers to an increase of intracellular fat in the liver and is defined when ≥5% of the weight of the liver is intrahepatic fat 3.
It is widely mischaracterized by both radiologists and sonographers as 'fatty infiltration' but the fat is in the hepatocytes and not in the extracellular matrix.
On imaging grounds, it can broadly be divided into two groups.
A third form, multifocal nodular hepatic steatosis is also rarely seen.
Ultrasound B-mode imaging is preferred as the first-line diagnostic modality for hepatic steatosis because of its wide availability, low cost, non-invasive, does not expose to ionizing radiation, repeatable, and well accepted by patients 2.
- 1. Okka W. Hamer, Diego A. Aguirre, Giovanna Casola, Joel E. Lavine, Matthias Woenckhaus, Claude B. Sirlin. Fatty Liver: Imaging Patterns and Pitfalls1. (2006) RadioGraphics. 26 (6): 1637-53. doi:10.1148/rg.266065004 - Pubmed
- 2. Ferraioli G & Monteiro L. Ultrasound-Based Techniques for the Diagnosis of Liver Steatosis. WJG. 2019;25(40):6053-62. doi:10.3748/wjg.v25.i40.6053 - Pubmed
- 3. Nassir F, Rector R, Hammoud G, Ibdah J. Pathogenesis and Prevention of Hepatic Steatosis. Gastroenterol Hepatol (N Y). 2015;11(3):167-75. PMC4836586 - Pubmed