Hepatomegaly refers to an increase in size or enlargement of the liver


Hepatomegaly can result from a vast range of pathology including, but not limited to, the following:

Assessment of liver size in commonly made on ultrasound or CT, although gross hepatomegaly may be apparent on abdominal radiograph.

For the adult liver:

  • midclavicular line averages 10-12.5 cm in craniocaudal length 2
    •  a liver that is longer than 15.5 cm in the midclavicular line is considered enlarged
  • average transverse diameter is 20-23 cm at the area of the upper pole of the right kidney 2

In practice, however, assessment is often subjective.

Features that support hepatomegaly include 1:

  • extension of the right lobe inferior to the lower pole of the right kidney
  • rounding of the hepatic inferior border
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Article information

rID: 6213
Section: Gamuts
Synonyms or Alternate Spellings:
  • Hepatic enlargement
  • Enlarged liver
  • Liver enlargement

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Cases and figures

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    Case 1: hepatomegaly on abdominal radiograph
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    Case 2
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    Case 3: CML with hepatosplenomegaly
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    Case 4: due to metastases
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    Case 5: metastases displacing bowel inferiorly
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    Case 6: myelofibrosis
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