Herder risk model

Last revised by Henry Knipe on 28 May 2020

British Thoracic Society (BTS) guidelines for pulmonary nodules1 recommend the application of the Herder risk model in predicting malignancy in pulmonary nodules.

The Herder model 2 predicts the risk of malignancy in solid pulmonary nodules using patient characteristics, nodules characteristics, and the degree of FDG uptake on PET-CT.

Using the Herder model, pulmonary nodule FDG uptake is classified into four categories. Herder et al did not suggest specific objective values for each level, however, other studies have ref. The BTS recommend using the following scale:

  • no uptake: uptake indiscernible from background lung tissue
  • faint uptake: uptake less than or equal to mediastinal blood pool
  • moderate uptake: uptake greater than mediastinal blood pool
  • intense uptake: uptake markedly greater than mediastinal blood pool (not strictly defined but 3x mediastinal blood pool would be considered intense)

ADVERTISEMENT: Supporters see fewer/no ads

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.