Hereditary renal cancer syndromes

Despite the vast majority of renal cancers being sporadic, there are a number of hereditary renal cancer syndromes:

• von Hippel Lindau syndrome: predominantly clear cell type
• tuberous sclerosis: predominantly clear cell type
• hereditary leiomyomataleiomyomatosis and renal cell cancer syndromecarcinoma: described in ISUP Vancouver classification ³²
• Birt-Hogg-Dube syndrome: predominantly chromophobe renal cell cancer (also associated with oncocytic adenomas)
• hereditary papillary renal cell cancer type 1: papillary type I
• hereditary non-polyposis colon cancer (Lynch type II): predominantly transitional cell carcinoma of the renal pelvis
• hereditary renal oncocytoma
• sickle cell anaemia: medullary renal carcinoma

See also

• renal cell carcinoma