HIV associated follicular bronchiolitis

Last revised by Rohit Sharma on 17 Jan 2022

HIV associated follicular bronchiolitis is a form of bronchiolitis that occurs in those with HIV.

It has been described in both HIV-positive children and adults.

It is manifested by bronchial-associated lymphoid tissue hyperplasia thought to be due to repetitive antigen stimulation and polyclonal lymphoid expansion. When associated with follicular bronchiolitis, this histopathological pattern is limited to the peribronchiolar area, whereas in lymphoid interstitial pneumonia it extends into the interstitium.

Computed tomography usually shows small (<3 mm) centrilobular nodules and often demonstrates peribronchial nodules. Some patients may have ground-glass changes 3.

It can have a variable prognosis. However, it can resolve with antiretroviral therapy (ART). 

Possible considerations include

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