HIV-associated salivary gland disease
Updates to Article Attributes
Body
was changed:
Parotid enlargement (a.k.a parotidomegaly) has a wide differentials. Causes include inflammatory, infective, Immune, neoplastic, infiltrative, and congenital causes. HIV related disease generally presents with dry mouth with swelling of the major salivary glands.
Clinical presentation
Victims frequently present with signs of facial swelling, fever and myalgias
Histology:
Benign lymphoepithelial/myoepithelial lesion comprising of an intranodal cysts lined with epithelial cells
Radiological features:
Radiological features are non specific
US:
- Numerous hypoattenuating / anechoic regions without posterior acoustic enhancement
- anechoic cysts
MR/CT :
- parotid enlargement bilaterally with intraglandular cystic and solid masses
- Cervical lymph nodal enlargement
-<p><strong>Parotid enlargement</strong> (a.k.a <strong>parotidomegaly</strong>) has a wide differentials. Causes include inflammatory, infective, Immune, neoplastic, infiltrative, and congenital causes. HIV related disease generally presents with dry mouth with swelling of the major <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/salivary-gland">salivary glands</a>.</p><p> </p><h4>Histology:</h4><p>Benign lymphoepithelial/myoepithelial lesion comprising of an intranodal cysts lined with epithelial cells</p><h4>Radiological features:</h4><h4>- +<p><strong>Parotid enlargement</strong> (a.k.a <strong>parotidomegaly</strong>) has a wide differentials. Causes include inflammatory, infective, Immune, neoplastic, infiltrative, and congenital causes. HIV related disease generally presents with dry mouth with swelling of the major <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/salivary-gland">salivary glands</a>.</p><h4>Clinical presentation</h4><p>Victims frequently present with signs of facial swelling, fever and myalgias</p><h4>Histology:</h4><p>Benign lymphoepithelial/myoepithelial lesion comprising of an intranodal cysts lined with epithelial cells</p><h4>Radiological features:</h4><p>Radiological features are non specific</p><h4>
References changed:
- 4. Nizamuddin, Imran, Koulen, Peter, McArthur, Carole P.. Contribution of HIV Infection, AIDS, and Antiretroviral Therapy to Exocrine Pathogenesis in Salivary and Lacrimal Glands. (2018) International Journal of Molecular Sciences. 19 (9): 2747. <a href="https://doi.org/10.3390/ijms19092747">doi:10.3390/ijms19092747</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/30217034">Pubmed</a> <span class="ref_v4"></span>