It usually manifests as flaccid paralysis of an extremity.
Areas of high T2 signal intensity in one or both anterior horns in the cervical spine may be seen.
Treatment and prognosis
Prognosis is usually not good and patients may remain paralyzed permanently, however, treatment with IV gamma globulin with a good response has been reported in some cases 3.
- 1. Hayashi F, Hayashi S, Matsuse D, Yamasaki R, Yonekura K, Kira JI. Hopkins syndrome following the first episode of bronchial asthma associated with enterovirus D68: a case report. (2018) BMC neurology. 18 (1): 71. doi:10.1186/s12883-018-1075-7 - Pubmed
- 2. Arita J, Nakae Y, Matsushima H, Maekawa K. Hopkins syndrome: T2-weighted high intensity of anterior horn on spinal MR imaging. (1995) Pediatric neurology. 13 (3): 263-5. Pubmed
- 3. Cohen HA, Ashkenasi A, Ring H, Weiss R, Wolach B, Paret G, Barzilai A. Poliomyelitis-like syndrome following asthmatic attack (Hopkins' syndrome)--recovery associated with i.v. gamma globulin treatment. (1998) Infection. 26 (4): 247-9. Pubmed