Human herpesvirus 6 encephalitis
Last revised by Daniel J Bell on 3 Nov 2021
Citation, DOI, disclosures and article data
Citation:
Di Muzio B, Bell D, Murphy A, et al. Human herpesvirus 6 encephalitis. Reference article, Radiopaedia.org (Accessed on 08 Dec 2023) https://doi.org/10.53347/rID-36613
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rID:
36613
Article created:
Disclosures:
At the time the article was created Bruno Di Muzio had no recorded disclosures.
View Bruno Di Muzio's current disclosuresLast revised:
3 Nov 2021, Daniel J Bell ◉
Disclosures:
At the time the article was last revised Daniel J Bell had no recorded disclosures.
View Daniel J Bell's current disclosuresRevisions:
9 times, by 7 contributors - see full revision history and disclosures
Systems:
Synonyms:
- HHV-6 encephalitis
Human herpesvirus 6 (HHV-6) encephalitis is a rare CNS infection due to human herpesvirus 6 reactivation in immunosuppressed patients, especially in those following a hematopoietic cell transplant who develop a characteristic limbic encephalitis syndrome with MRI signal intensity abnormalities of the mesial temporal lobe 1.
Studies have been conducted to investigate possible associations of HHV-6 with mesial temporal lobe epilepsy (mesial temporal sclerosis) 2 and multiple sclerosis (MS) 1,3.
References
- 1. Gewurz BE, Marty FM, Baden LR et-al. Human herpesvirus 6 encephalitis. Curr Infect Dis Rep. 2010;10 (4): 292-9. Pubmed citation
- 2. Fotheringham J, Donati D, Akhyani N et-al. Association of human herpesvirus-6B with mesial temporal lobe epilepsy. PLoS Med. 2007;4 (5): e180. doi:10.1371/journal.pmed.0040180 - Free text at pubmed - Pubmed citation
- 3. Kimberlin DW, Whitley RJ. Human herpesvirus-6: neurologic implications of a newly-described viral pathogen. J. Neurovirol. 1999;4 (5): 474-85. Pubmed citation
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