Human herpesvirus 6 encephalitis

Last revised by Daniel J Bell on 3 Nov 2021

Human herpesvirus 6 (HHV-6) encephalitis is a rare CNS infection due to human herpesvirus 6 reactivation in immunosuppressed patients, especially in those following a hematopoietic cell transplant who develop a characteristic limbic encephalitis syndrome with MRI signal intensity abnormalities of the mesial temporal lobe 1

Studies have been conducted to investigate possible associations of HHV-6 with mesial temporal lobe epilepsy (mesial temporal sclerosis2 and multiple sclerosis (MS) 1,3.

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Cases and figures

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