Human metapneumovirus pulmonary infection
Updates to Article Attributes
Human metapneumovirus (hMPV) pulmonary infection is a recently detected condition reported to cause mild to severe respiratory tract infection, particularly in children, immunocompromised patients, and the elderly 6.
Pathology
Human metapneumovirus (HMPV), is an RNA virus and was first described in 2001. It is a common pathogen and can cause acute viral respiratory tract infections in all age groups.
IgG antibodies against HMPV have been detected in up to 100% of persons with reinfection being common 1.
Radiographic features
Chest x-ray
Changes can be nonspecificnon-specific and be of a variable pattern. In children according to one study 2:
parahilar /
peri-bronchovascularperibronchovascular opacities were the most commonly observed abnormality (87% of children with HMPV).lungs may also hyperinflated
atelectasis (40%) and consolidation (18%) have been less frequently described.
CT
NonspecificNon-specific changes with ground-glass opacity have been the most commonly reported findings with nodular consolidation described in a lesser number of patients 3.
Involvement can often be bilateral.
-<p><strong>Human metapneumovirus (hMPV) pulmonary infection </strong>is a recently detected condition reported to cause mild to severe respiratory tract infection, particularly in children, immunocompromised patients, and the elderly <sup>6</sup>.</p><h4>Pathology</h4><p><a href="/articles/human-metapneumovirus">Human metapneumovirus</a> (HMPV), is an RNA virus and was first described in 2001. It is a common pathogen and can cause acute <a href="/articles/viral-respiratory-tract-infections">viral respiratory tract infections</a> in all age groups.</p><p>IgG antibodies against HMPV have been detected in up to 100% of persons with reinfection being common <sup>1</sup>.</p><h4>Radiographic features</h4><h5>Chest x-ray</h5><p>Changes can be nonspecific and be of a variable pattern. In <strong>children</strong> according to one study <sup>2</sup>:</p><ul>-<li>parahilar / peri-bronchovascular opacities were the most commonly observed abnormality (87% of children with HMPV).</li>-<li>lungs may also hyperinflated</li>-<li>atelectasis (40%) and consolidation (18%) have been less frequently described. </li>-</ul><h5>CT </h5><p>Nonspecific changes with ground-glass opacity have been the most commonly reported findings with nodular consolidation described in a lesser number of patients <sup>3</sup>. </p><p>Involvement can often be bilateral.</p>- +<p><strong>Human metapneumovirus (hMPV) pulmonary infection </strong>is a recently detected condition reported to cause mild to severe respiratory tract infection, particularly in children, immunocompromised patients, and the elderly <sup>6</sup>.</p><h4>Pathology</h4><p><a href="/articles/human-metapneumovirus">Human metapneumovirus</a> (HMPV), is an RNA virus and was first described in 2001. It is a common pathogen and can cause acute <a href="/articles/viral-respiratory-tract-infections">viral respiratory tract infections</a> in all age groups.</p><p>IgG antibodies against HMPV have been detected in up to 100% of persons with reinfection being common <sup>1</sup>.</p><h4>Radiographic features</h4><h5>Chest x-ray</h5><p>Changes can be non-specific and be of a variable pattern. In <strong>children</strong> according to one study <sup>2</sup>:</p><ul>
- +<li><p>parahilar / peribronchovascular opacities were the most commonly observed abnormality (87% of children with HMPV).</p></li>
- +<li><p>lungs may also hyperinflated</p></li>
- +<li><p>atelectasis (40%) and consolidation (18%) have been less frequently described. </p></li>
- +</ul><h5>CT </h5><p>Non-specific changes with ground-glass opacity have been the most commonly reported findings with nodular consolidation described in a lesser number of patients <sup>3</sup>. </p><p>Involvement can often be bilateral.</p>
Tags changed:
- cases (2)
Systems changed:
- Chest