Citation, DOI, disclosures and article data
Citation:
Hacking C, Knipe H, Hyperacute lung transplant rejection. Reference article, Radiopaedia.org (Accessed on 14 Jan 2025) https://doi.org/10.53347/rID-74337
Hyperacute lung transplant rejection is a rare, rapid and often fatal form of early post lung transplant complications.
Hyperacute rejection occurs in the first few hours after reperfusion of the allograft lungs.
Following recommencement of blood flow into the allograft, recipient preformed antibodies to donor lung antigens are released and rapidly cause pulmonary edema. Intraoperative pulmonary edema has been observed 2.
Plain radiograph and CT
Treatment and prognosis
Plasmapheresis has been trialled. Mortality is very high.
-
1. Jokerst C, Sirajuddin A, Mohammed TL. Imaging the Complications of Lung Transplantation. (2016) Radiologic clinics of North America. 54 (2): 355-73. doi:10.1016/j.rcl.2015.09.014 - Pubmed
-
2. Diez Martinez P, Pakkal M, Prenovault J, Chevrier MC, Chalaoui J, Gorgos A, Ferraro P, Poirier C, Chartrand-Lefebvre C. Postoperative imaging after lung transplantation. (2013) Clinical imaging. 37 (4): 617-23. doi:10.1016/j.clinimag.2013.02.008 - Pubmed
-
3. Yuen Li Ng, Narinder Paul, Demetris Patsios, Anna Walsham, Tae-Bong Chung, Shaf Keshavjee, Gordon Weisbrod. Imaging of Lung Transplantation: Review. (2012) American Journal of Roentgenology. 192 (3 Suppl): S1-13, quiz S14-9. doi:10.2214/AJR.07.7061 - Pubmed
-
4. Mayil S. Krishnam, Robert D. Suh, Anderanik Tomasian, Jonathan G. Goldin, Chi Lai, Kathleen Brown, Poonam Batra, Denise R. Aberle. Postoperative Complications of Lung Transplantation: Radiologic Findings along a Time Continuum1. (2007) RadioGraphics. 27 (4): 957-74. doi:10.1148/rg.274065141 - Pubmed
-
5. Céline Habre, Paola M. Soccal, Frédéric Triponez, John-David Aubert, Thorsten Krueger, Steve P. Martin, Joanna Gariani, Jean-Claude Pache, Frédéric Lador, Xavier Montet, Anne-Lise Hachulla. Radiological findings of complications after lung transplantation. (2018) Insights into Imaging. 9 (5): 709. doi:10.1007/s13244-018-0647-9 - Pubmed
Promoted articles (advertising)
Unable to process the form. Check for errors and try again.