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Citation:
Staziaki P, Feger J, Foster T, Hypoattenuated leaflet thickening. Reference article, Radiopaedia.org (Accessed on 25 Apr 2024) https://doi.org/10.53347/rID-78750
Hypoattenuated leaflet thickening (HALT) is an imaging feature seen on cardiac CT in the setting of subclinical leaflet thrombosis of prosthetic heart valves.
In the setting of surgical or transcatheter aortic valve replacement (TAVR), the evaluation for hypoattenuated leaflet thickening should be conducted in the diastolic phase after leaflet coaptation has been visualized 1-3.
On cross-sectional para-axial images, it is a hypoattenuating focal area seen on a valve leaflet that begins at the leaflet insertion on the valve frame and might be associated with reduced leaflet motion 1,3.
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1. Makkar RR, Fontana G, Jilaihawi H, Chakravarty T, Kofoed KF, De Backer O, Asch FM, Ruiz CE, Olsen NT, Trento A, Friedman J, Berman D, Cheng W, Kashif M, Jelnin V, Kliger CA, Guo H, Pichard AD, Weissman NJ, Kapadia S, Manasse E, Bhatt DL, Leon MB, Søndergaard L. Possible Subclinical Leaflet Thrombosis in Bioprosthetic Aortic Valves. (2015) The New England journal of medicine. 373 (21): 2015-24. doi:10.1056/NEJMoa1509233 - Pubmed
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2. Goel K, Lindman BR. Hypoattenuated Leaflet Thickening After Transcatheter Aortic Valve Replacement: Expanding the Evidence Base but Questions Remain. (2019) Circulation. Cardiovascular imaging. 12 (12): e010151. doi:10.1161/CIRCIMAGING.119.010151 - Pubmed
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3. Jilaihawi H, Asch F, Manasse E et al. Systematic CT Methodology for the Evaluation of Subclinical Leaflet Thrombosis. JACC Cardiovasc Imaging. 2017;10(4):461-70. doi:10.1016/j.jcmg.2017.02.005 - Pubmed
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