Hypoparathyroidism

Dr Henry Knipe et al.

Hypoparathyroidism results from reduced secretion of parathyroid hormone by the parathyroid glands. It results in hypocalcaemia. 

  • tetany: peripheral paresthesia, carpopedal spasm, seizures
  • emotional lability, depression and anxiety, psychosis
  • short stature

There are a number of causes for hypoparathyroidism 1:

  • iatrogenic, e.g. post parathyroidectomy or thyroidectomy
  • congenital absence of the parathyroid glands, which may be syndromic in thymic aplasia, or 22q11.2 deletion syndrome (a.k.a. DiGeorge syndrome)
  • familial, e.g. autoimmune polyendocrine syndrome type 1
  • idiopathic (probably autoimmune-mediated destruction)
Markers
  • parathyroid hormone (PTH) level: low
  • serum phosphate level: high
  • serum calcium level: low  
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Article information

rID: 39959
System: Head & Neck
Section: Pathology
Synonyms or Alternate Spellings:
  • Low thyroid levels

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