Hypophosphatasia

Hypophosphatasia (HP) refers to a rare metabolic disorder characterised by deficient serum alkaline phosphatase activity. The effects of hypophosphatasia are primary seen in the skeletal system. The condition have a extreme variation in clinical expression (see sub types)

This is best discussed according specific sub types.

Sub types

Hypophosphatasia can be divided into several groups (at least 6 types 6,8) primarily according to age at presentation 3,6

Skeletal manifestations

Some of the skeletal features may be common to across types and include 4:

  • effects of hypercalcaemia
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Article Information

rID: 13871
Tag: cases
Synonyms or Alternate Spellings:
  • Congenital hypophosphatasia
  • Hypophosphatasia: general

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