Hypospadias

Dr Aditya Shetty and Radswiki et al.

Hypospadias refers to type of congential malformation affecting the male external genitalia.

The estimated prevalence is ~2 (range 0.2-4.1) per 1000 live births.

The urethral meatus is abnormally positioned proximally and ventrally to its normal position.

It is thought to be due to failure of fusion of the urethral groove secondary to either testosterone deficiency or end organ insensitivity to testosterone. 

Associations

Associated anomalies are common and include:

Syndromic associations include:

Antenatal ultrasound

May identify anomalous distal morphology of the penis (where it loses its pointed end, which becomes blunter or straighter, in the form of a squashed cone).

There may be small lateral folds seen as longitudinal echogenic lines (dermal remains of the prepuce).

There may be a ventral curvature of the distal penis, extension of the penile glans beyond the prepuce, and evidence of fetal micturition in a plane perpendicular to the penile shaft 3.

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Article information

rID: 14596
System: Urogenital
Section: Pathology
Tags: cases, urology
Synonyms or Alternate Spellings:
  • Hypospadia

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