Idiopathic scrotal calcinosis (ISC), sometimes called dystrophic scrotal calcinosis, is a rare benign condition characterized by superficial calcifications within the skin of the scrotum of unclear aetiology, typically affecting men aged 20-40 years. The condition is primarily cosmetic, but may recur following excision of the calcified bodies.
Proposed aetiologies for idiopathic scrotal calcinosis includes epidermal inclusion cysts which calcify, necrosis and degeneration of the dartos muscle leading to dystrophic calcifications, and excessive discharge in eccrine epithelial cysts which leads to calcification of the debris build up in the lumina.
- 1. Pompeo A, Molina WR, Pohlman GD et-al. Idiopathic scrotal calcinosis: A rare entity and a review of the literature. Can Urol Assoc J. 2013;7 (5-6): E439-41. doi:10.5489/cuaj.1387 - Free text at pubmed - Pubmed citation
- 2. Khallouk A, Yazami OE, Mellas S et-al. Idiopathic scrotal calcinosis: a non-elucidated pathogenesis and its surgical treatment. Rev Urol. 2011;13 (2): 95-7. Free text at pubmed - Pubmed citation