Idiopathic scrotal calcinosis

Idiopathic scrotal calcinosis (ISC), sometimes called dystrophic scrotal calcinosis,  is a rare benign condition characterized by superficial calcifications within the skin of the scrotum of unclear etiology, typically affecting men aged 20-40. The condition is primarily cosmetic, but may recur following excision of the calcified bodies.

Pathophysiology

Proposed etiologies for ISC includes epidermal inclusion cysts which calcify, necrosis and degeneration of the dartos muscle leading to dystrophic calcifications, and excessive discharge in eccrine epithelial cysts which leads to calcification of the debris build up in the lumina. 

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Article information

rID: 42476
System: Urogenital
Section: Pathology
Tag: stub
Synonyms or Alternate Spellings:
  • Dystrophic scrotal calcinosis
  • Idiopathic scrotal calcinosis (ISC)

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