Infiltrating syringomatous adenoma of the nipple

Last revised by Daniel J Bell on 24 Feb 2018

Citation, DOI, disclosures and article data

Citation:

Skandhan A, Bell D, Tatco V, et al. Infiltrating syringomatous adenoma of the nipple. Reference article, Radiopaedia.org (Accessed on 16 Apr 2024) https://doi.org/10.53347/rID-28598

DOI:

https://doi.org/10.53347/rID-28598

Permalink:

https://radiopaedia.org/articles/28598

rID:

28598

Article created:

1 Apr 2014, Avni K P Skandhan

Disclosures:

At the time the article was created Avni K P Skandhan had no recorded disclosures.

View Avni K P Skandhan's current disclosures

Last revised:

24 Feb 2018, Daniel J Bell ◉

Disclosures:

At the time the article was last revised Daniel J Bell had no recorded disclosures.

View Daniel J Bell's current disclosures

Revisions:

5 times, by 5 contributors - see full revision history and disclosures

Systems:

Breast

Tags:

breast

Synonyms:

Syringomatous tumor of the nipple

Infiltrating syringomatous adenoma of the nipple is a relatively rare, benign dermal neoplasm of the areola and nipple.

Syringomatous adenomas of the nipple usually present as unilateral 1 to 3 cm firm lesion in the subareolar or nipple region of the breast. Tenderness, itchiness, crusting, ulceration, and nipple discharge or nipple inversion may be present. Average age at the time of presentation is 40 years of age.

Pathology

Gross

Dermal nodule in the subareolar location.

Histologically

Epidermal acanthosis and pseudoepitheliomatous hyperplasia. Dermal infiltrates of curved, ductular structures lined by flattened-to-cuboidal cells, often with proteinaceous debris and skin-type keratin seen in their lumens. Keratinous cysts are often seen ³.