Inflammatory myofibroblastic tumor
Last revised by Yaïr Glick on 23 Feb 2022
Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Glick Y, Jones J, et al. Inflammatory myofibroblastic tumor. Reference article, Radiopaedia.org (Accessed on 03 Dec 2023) https://doi.org/10.53347/rID-11033
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rID:
11033
Article created:
10 Oct 2010, Yuranga Weerakkody ◉
Disclosures:
At the time the article was created Yuranga Weerakkody had no recorded disclosures.
View Yuranga Weerakkody's current disclosuresLast revised:
23 Feb 2022, Yaïr Glick ◉
Disclosures:
At the time the article was last revised Yaïr Glick had no recorded disclosures.
View Yaïr Glick's current disclosuresRevisions:
12 times, by 7 contributors - see full revision history and disclosures
Systems:
Tags:
Synonyms:
- Inflammatory myofibroblastic tumour (IMT)
- Plasma cell granuloma
- Inflammatory myofibroblastic tumours
- Inflammatory myofibroblastic tumor
- Inflammatory myofibroblastic tumors
- Plasma cell granulomas
- Plasma-cell granuloma
- Plasma-cell granulomas
Inflammatory myofibroblastic tumors (IMT), also known as plasma cell granulomas, are rare neoplasms that have a diverse spectrum of biological behavior.
On this page:
Terminology
These tumors were previously referred to as inflammatory pseudotumor.
Epidemiology
They can occur at any age and there is currently no recognized gender predilection.
Pathology
Composed of spindle cells (key feature) with a variable infiltrate of inflammatory cells and fibrous tissue. They can occur at numerous sites:
- more common 3
- lung: inflammatory myofibroblastic tumor of the lung
- abdominal cavity
- retroperitoneum
- extremities
- less common
- liver 8
- spleen 10
- genitourinary tract 6
Radiographic features
Imaging characteristics depend on the organ of involvement:
References
- 1. Kim SJ, Kim WS, Cheon JE et-al. Inflammatory myofibroblastic tumors of the abdomen as mimickers of malignancy: imaging features in nine children. AJR Am J Roentgenol. 2009;193 (5): 1419-24. doi:10.2214/AJR.09.2433 - Pubmed citation
- 2. Gleason BC, Hornick JL. Inflammatory myofibroblastic tumours: where are we now? J. Clin. Pathol. 2008;61 (4): 428-37. doi:10.1136/jcp.2007.049387 - Pubmed citation
- 3. Lai V, Wong YC, Lam WY et-al. Inflammatory myofibroblastic tumor of the nasal cavity. AJNR Am J Neuroradiol. 2007;28 (1): 135-7. AJNR Am J Neuroradiol (full text) - Pubmed citation
- 4.Van den heuvel DA, Keijsers RG, Van es HW et-al. Invasive inflammatory myofibroblastic tumor of the lung. J Thorac Oncol. 2009;4 (7): 923-6. doi:10.1097/JTO.0b013e3181a76e28 - Pubmed citation
- 5. Rasalkar DD, Chu WC, To KF et-al. Radiological appearance of inflammatory myofibroblastic tumour. Pediatr Blood Cancer. 2010;54 (7): 1029-31. doi:10.1002/pbc.22391 - Pubmed citation
- 6. Hosokawa C, Tsubakimoto M, Inoue Y et-al. Radiologic features of inflammatory pseudotumor of the ureter. AJR Am J Roentgenol. 2007;188 (2): W202-5. doi:10.2214/AJR.05.0578 - Pubmed citation
- 7. Coffin CM, Dehner LP, Meis-kindblom JM. Inflammatory myofibroblastic tumor, inflammatory fibrosarcoma, and related lesions: an historical review with differential diagnostic considerations. Semin Diagn Pathol. 1998;15 (2): 102-10. - Pubmed citation
- 8 .Venkataraman S, Semelka RC, Braga L et-al. Inflammatory myofibroblastic tumor of the hepatobiliary system: report of MR imaging appearance in four patients. Radiology. 2003;227 (3): 758-63. doi:10.1148/radiol.2273020572 - Pubmed citation
- 9. Palaskar S, Koshti S, Maralingannavar M et-al. Inflammatory myofibroblastic tumor. Contemp Clin Dent. 2011;2 (4): 274-7. doi:10.4103/0976-237X.91787 - Free text at pubmed - Pubmed citation
- 10. Lee HJ, Kim JW, Hong JH, Kim GS, Shin SS, Heo SH, Lim HS, Hur YH, Seon HJ, Jeong YY. Cross-sectional Imaging of Splenic Lesions: RadioGraphics Fundamentals | Online Presentation. (2018) Radiographics : a review publication of the Radiological Society of North America, Inc. 38 (2): 435-436. doi:10.1148/rg.2018170119 - Pubmed
Incoming Links
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