An inflammatory pseudopolyp is an island of normal colonic mucosa which only appears raised because it is surrounded by atrophic tissue (denuded ulcerative mucosa). It is seen in long-standing ulcerative colitis.
It must be distinguished from inflammatory polyps, which are regions of inflamed and elevated mucosa surrounded by granular mucosa.
On CT scan or barium enema, inflammatory pseudopolyps appear as innumerable polypoid colonic filling defects. These area are usually enhancing on contrast-enhanced CT scan.
- 1. Ajioka Y, Nishikura K, Watanabe G. [Pathomorphology of ulcerative colitis]. Nippon Rinsho. 2005;63 (5): 763-9. - Pubmed citation
- 2. Choi YS, Suh JP, Lee IT et-al. Regression of giant pseudopolyps in inflammatory bowel disease. J Crohns Colitis. 2012;6 (2): 240-3. doi:10.1016/j.crohns.2011.08.007 - Pubmed citation