Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Bell D, Luong D, Inspissated secretions. Reference article, Radiopaedia.org (Accessed on 07 Dec 2024) https://radiopaedia.org/articles/88386
Inspissated secretions refers to thickened secretions with increased viscosity within ducts or body cavities (usually nasal, paranasal sinus, oral or ductal) that usually become thickened by dehydration (typically a chronic process). The secretions can then cause obstruction to respective airways or ducts. Some inspissated secretions may become calcified resulting in dystrophic calcification.
Radiographic features
CT
May be hyper-attenuating due to calcific components
MRI
Tend to be low signal on most sequences 3.
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1. Wood K et.al. Inspissated secretions: a life-threatening complication of prolonged noninvasive ventilation. (2000) Respiratory care. doi: - Pubmed
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2. Flanagan D. Inspissated oral secretions and a review of their clinical, biological, and physiological significance. (2012) Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry. 32 (3): 99-104. doi:10.1111/j.1754-4505.2012.00241.x - Pubmed
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3. Dillon W, Som P, Fullerton G. Hypointense MR Signal in Chronically Inspissated Sinonasal Secretions. Radiology. 1990;174(1):73-8. doi:10.1148/radiology.174.1.2294574
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