Inter twin membrane folding

Inter twin membrane folding is an observation where the inter twin membrane in a twin pregnancy appears as being folded. It is sometimes used as a predictor for the development of twin to twin transfusion syndrome. It occurs as a result of amniotic fluid discordance.

Some reports suggest that  folding of the inter-twin membrane occurs in about one-quarter of monochorionic twins where in ~43-50% half of these there can be subsequent development of twin-to-twin transfusion syndrome 1-2.

Share article

Article information

rID: 15057
System: Obstetrics
Tags: stub, cases
Synonyms or Alternate Spellings:
  • Folding of the inter-twin membrane
  • Folding of intertwin membrane
  • Folding of inter-twin membrane