International Society of Urological Pathology Vancouver classification of renal neoplasia (historical)

The International Society of Urological Pathology Vancouver classification of renal neoplasia is a now-outdated classification of renal tumors published in 2013. It formed the basis for the WHO classification of tumors of the kidney published in 2016. For reference, the ISUP Vancouver classification is presented below.

Classification

Renal cell tumors

• papillary adenoma

• oncocytoma

• clear cell renal cell carcinoma

  • Including multilocular cystic clear cell renal cell neoplasm of low malignant potential*

• papillary renal cell carcinoma

• chromophobe renal cell carcinoma

  • including hybrid oncocytic chromophobe tumor*

• carcinoma of the collecting ducts of Bellini

• renal medullary carcinoma

• MiT family translocation renal cell carcinoma*

  • Xp11 translocation renal cell carcinoma

  • t(6;11) renal cell carcinoma*

• carcinoma associated with neuroblastoma

• mucinous tubular and spindle cell carcinoma

• tubulocystic renal cell carcinoma*

• acquired cystic disease associated renal cell carcinoma*

• clear cell (tubulo) papillary renal cell carcinoma*

• hereditary leiomyomatosis renal cell carcinoma syndrome-associated renal cell carcinoma*

• renal cell carcinoma, unclassified

Metanephric tumors

• metanephric adenoma

• metanephric adenofibroma

• metanephric stromal tumor

Nephroblastic tumors

• nephrogenic rests

• nephroblastoma

  • inc. cystic partially differentiated nephroblastoma

Mesenchymal tumors

• occurring mainly in children

  • clear cell sarcoma

  • rhabdoid tumor

  • congenital mesoblastic nephroma

  • ossifying renal tumor of infants

• occurring mainly in adults

  • renal leiomyosarcoma (including renal vein)

  • renal angiosarcoma

  • renal rhabdomyosarcoma

  • malignant fibrous histiocytoma

  • heamangiopericytoma of the kidney

  • osteosarcoma

  • synovial sarcoma*

  • angiomyolipoma

    • epithelioid angiomyolipoma*

  • leiomyoma

  • hemangioma

  • lymphangioma

  • juxtaglomerular cell tumor

  • renomedullary interstitial cell tumor

  • schwannoma

  • solitary fibrous tumor

Mixed mesenchymal and epithelial tumors

• cystic nephroma / mixed epithelial stromal tumor

Neuroendocrine tumors

• carcinoid (low-grade neuroendocrine tumor)

• neuroendocrine carcinoma (high-grade neuroendocrine tumor)

• primitive neuroectodermal tumor

• neuroblastoma

• pheochromocytoma

Hematopoietic and lymphoid tumors

• renal lymphoma

• leukemia

• plasmacytoma

Germ cell tumors

• teratoma

• choriocarcinoma

Metastatic tumors

Other tumors

*Additions and changes in terminology or position in classification since the 2004 revision of the World Health Organizatiοn Classification of Renal Tumors.