International Society of Urological Pathology Vancouver classification of renal neoplasia (historical)

The International Society of Urological Pathology Vancouver classification of renal neoplasia is a now-outdated classification of renal tumours published in 2013. It formed the basis for the WHO classification of tumours of the kidney published in 2016. For reference, the ISUP Vancouver classification is presented below.

Classification

Renal cell tumours

• papillary adenoma

• oncocytoma

• clear cell renal cell carcinoma

  • Including multilocular cystic clear cell renal cell neoplasm of low malignant potential*

• papillary renal cell carcinoma

• chromophobe renal cell carcinoma

  • including hybrid oncocytic chromophobe tumour*

• carcinoma of the collecting ducts of Bellini

• renal medullary carcinoma

• MiT family translocation renal cell carcinoma*

  • Xp11 translocation renal cell carcinoma

  • t(6;11) renal cell carcinoma*

• carcinoma associated with neuroblastoma

• mucinous tubular and spindle cell carcinoma

• tubulocystic renal cell carcinoma*

• acquired cystic disease associated renal cell carcinoma*

• clear cell (tubulo) papillary renal cell carcinoma*

• hereditary leiomyomatosis renal cell carcinoma syndrome-associated renal cell carcinoma*

• renal cell carcinoma, unclassified

Metanephric tumours

• metanephric adenoma

• metanephric adenofibroma

• metanephric stromal tumour

Nephroblastic tumours

• nephrogenic rests

• nephroblastoma

  • inc. cystic partially differentiated nephroblastoma

Mesenchymal tumours

• occurring mainly in children

  • clear cell sarcoma

  • rhabdoid tumour

  • congenital mesoblastic nephroma

  • ossifying renal tumour of infants

• occurring mainly in adults

  • renal leiomyosarcoma (including renal vein)

  • renal angiosarcoma

  • renal rhabdomyosarcoma

  • malignant fibrous histiocytoma

  • heamangiopericytoma of the kidney

  • osteosarcoma

  • synovial sarcoma*

  • angiomyolipoma

    • epithelioid angiomyolipoma*

  • leiomyoma

  • haemangioma

  • lymphangioma

  • juxtaglomerular cell tumour

  • renomedullary interstitial cell tumour

  • schwannoma

  • solitary fibrous tumour

Mixed mesenchymal and epithelial tumours

• cystic nephroma / mixed epithelial stromal tumour

Neuroendocrine tumours

• carcinoid (low-grade neuroendocrine tumour)

• neuroendocrine carcinoma (high-grade neuroendocrine tumour)

• primitive neuroectodermal tumour

• neuroblastoma

• phaeochromocytoma

Haematopoietic and lymphoid tumours

• renal lymphoma

• leukaemia

• plasmacytoma

Germ cell tumours

• teratoma

• choriocarcinoma

Metastatic tumours

Other tumours

*Additions and changes in terminology or position in classification since the 2004 revision of the World Health Organizatiοn Classification of Renal Tumours.