Intracranial choriocarcinoma

Intracranial choriocarcinomas are rare, accounting for only 5% of all pineal masses 2 and 10% of all intracranial germ cells tumors 1. Like other intracranial germ cell tumors, they are found both in the pineal and suprasellar region. Typically they have increased CSF and plasma b-HCG, which are helpful in establishing the diagnosis 2,3.

Radiographic features

MRI Brain

These tumors are highly vascular and have a propensity to hemorrhage (as do their metastases). If present blood products may be evident on MRI as signal drop-out and blooming on T2* sequences and intrinsic high T1 signal, which needs to be distinguished from calcification and fat respectively 2

They have a propensity to metastasize haematogenously 3.

Pineal region masses

The pineal region is anatomically complex and plays host to a number of unique masses and tumors as well as potentially affected by many entities seen more frequently elsewhere in the brain. 

General reading


Germ cell tumours
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Article information

rID: 6635
Tag: stub, cases
Synonyms or Alternate Spellings:
  • Primary intracranial choriocarcinoma

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