Intracranial embryonal carcinoma
Last revised by Frank Gaillard on 21 Oct 2021
Citation, DOI, disclosures and article data
Citation:
Gaillard F, Kang O, Intracranial embryonal carcinoma. Reference article, Radiopaedia.org (Accessed on 19 Apr 2024) https://doi.org/10.53347/rID-6636
rID:
6636
Article created:
Disclosures:
At the time the article was created Frank Gaillard had no recorded disclosures.
View Frank Gaillard's current disclosures
Last revised:
Disclosures:
At the time the article was last revised Frank Gaillard had no recorded disclosures.
View Frank Gaillard's current disclosures
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Systems:
An intracranial embryonal carcinoma is a relatively rare neoplasm and accounts for only 10% of all intracranial germ cell tumors 1. It is an aggressive tumor and has a propensity to metastasize systemically 2. A component of embryonal carcinoma is often found in mixed germ-cell tumors, in which case it is usually the most aggressive component, and dictates prognosis. CSF and plasma AFP and b-HCG may be elevated 1, but again this is not specific to this tumor.
References
- 1. Horowitz Michael Bruce and Walter A. Hall. “Central Nervous System Germinomas: A Review.” Arch Neurol 48, no. 6 (June 1, 1991): 652-657. doi:10.1001/archneur.1991.00530180110026.
- 2. Smirniotopoulos JG, EJ Rushing and H Mena. “Pineal region masses: differential diagnosis.” Radiographics 12, no. 3 (May 1, 1992): 577-596. [Link].
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