Intracranial translucency

Last revised by Rohit Sharma on 22 Oct 2022

Intracranial translucency (IT) is the ultrasound appearance of the fourth ventricle in mid-sagittal plane as seen on 11-13 week antenatal scan. It is used as a marker for neural tube defects. Its absence is reported in open spina bifida 1.

Radiographic features

Technique
  • the fetus must be in the mid-sagittal plane, the same plane for measurement of nuchal translucency and nasal bone, where the brainstem, fourth ventricle, and cisterna magna are identified

  • the anteroposterior diameter of the fourth ventricle is measured between two echogenic lines:

    • posterior border of the brainstem anteriorly

    • choroid plexus of the fourth ventricle posteriorly

The median value of intracranial translucency is between 1.5 mm to 2.5 mm for crown rump length (CRL) 45 mm to 84 mm respectively 2.

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