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The intrapleural or pleural space is the fluid-filled space in between the parietal and visceral layers of the pleura. In normal conditions it contains only a small amount of serous pleural fluid.
Rarely there may be anomalous communication of the pleural spaces anteriorly.
A pleural effusion is the pathological accumulation of pleural fluid, and when infected becomes an empyema.
The pleural space can also be affected by a number of malignancies:
When air leaks into the pleural space, a life threatening pneumothorax may develop.
- 1. Kuhlman JE, Singha NK. Complex disease of the pleural space: radiographic and CT evaluation. Radiographics. 1997;17 (1): 63-79. doi:10.1148/radiographics.17.1.9017800 - Pubmed citation