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Citation:
Dinkel J, Sharma R, El-Feky M, Ischemic type biliary lesions. Reference article, Radiopaedia.org (Accessed on 21 Mar 2023) https://doi.org/10.53347/rID-76415
Ischemic type biliary lesions (ITBL) is a term used to describe non-anastomotic intra- or extrahepatic bile duct strictures after primarily successful liver transplantation, when there is no evidence of perfusion restriction or other cause of bile duct damage (i.e organ rejection or recurrence of primary sclerosing cholangitis) 1,3.
It should be differentiated from ischemic biliary lesions (IBL) due to vascular complications of operation or intervention and strictures after prolongated ischemia, i.e. hepatic artery stenosis 1.
Radiographic features
Endoscopic retrograde cholangiography and percutaneous transhepatic cholangiography are seen as the gold standard in the diagnosis of ITBL 2. However, MRCP can be used to detect ischemic type biliary lesions and differentiate them from other biliary complications 3-5.
Imaging features are similar to other types of bile duct strictures, including intra- and extrahepatic bile duct stenosis with proximal dilatation.
- 1. Abdeldayem, H. and Allam, N., 2012. Liver Transplantation - Technical Issues And Complications. [ebook] Available at: [Accessed 21 April 2020].
- 2. Zoepf T, Maldonado-Lopez EJ, Hilgard P, Dechêne A, Malago M, Broelsch CE, Schlaak J, Gerken G. Diagnosis of biliary strictures after liver transplantation: which is the best tool?. (2005) World journal of gastroenterology. 11 (19): 2945-8. doi:10.3748/wjg.v11.i19.2945 - Pubmed
- 3. Collettini F, Kröncke TJ, Heidenhain C, Renz DM, de Bucourt M, Neuhaus P, Poellinger A. [Magnetic resonance cholangiographic (MRCP) features of ischemic-type biliary lesions (ITBL): a case-control study]. (2011) RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin. 183 (8): 714-20. doi:10.1055/s-0031-1273346 - Pubmed
- 4. Boraschi P, Donati F, Pacciardi F, Ghinolfi D, Falaschi F. Biliary complications after liver transplantation: Assessment with MR cholangiopancreatography and MR imaging at 3T device. (2018) European journal of radiology. 106: 46-55. doi:10.1016/j.ejrad.2018.07.009 - Pubmed
- 5. Kinner S, Dechêne A, Ladd SC, Zöpf T, de Dechêne EM, Gerken G, Lauenstein TC. Comparison of different MRCP techniques for the depiction of biliary complications after liver transplantation. (2010) European radiology. 20 (7): 1749-56. doi:10.1007/s00330-010-1714-x - Pubmed
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