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Iselin disease

Iselin disease is a benign and self-limiting condition, defined as apophysitis of the base of the 5th metatarsal.

It is most commonly seen in males with sport injuries and is often also seen in adolescents. 

It is due to repetitive traction of the peroneus brevis tendon at the site of its attachment. Predisposing factors are jumping and running.

  • obliquely oriented small bony fleck at the base of the 5th metatarsal which is best seen on oblique radiograph
  • apophyseal irregularity

Usually not considered essential for the diagnosis. But if performed may show:

  • T2/STIR: high signal intensity around base of 5th metatarsal due to bone marrow edema 6

First described by Hans Iselin (1878-1953) 8 a German surgeon working in Basel, Switzerland, in 1912 4,5.

On imaging consider:

Article information

rID: 25356
Synonyms or Alternate Spellings:
  • Iselin disease (ID)
  • Traction apophysitis of 5th metatarsal base
  • Traction apophysitis of base of 5th metatarsal
  • Apophysitis of 5th metatarsal
  • Iselin's disease
  • Traction apophysitis of 5th metatarsal

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Cases and figures

  • Case 1: plain film
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  • Case 1: MRI
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  • Case 2: with avulsion fracture
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