Revision 17 for 'Iselin disease'

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Iselin disease

Iselin disease (ID) is a benign and self-limiting condition, defined as apophysitis of the base of the 5th metatarsal.


It is most commonly seen in males with sport injuries and is often also seen in adolescents. 


It is due to repetitive traction of the peroneus brevis tendon at the site of its attachment. Predisposing factors are jumping and running.

Radiographic features

Plain radiograph
  • obliquely oriented small bony fleck at the base of the 5th metatarsal which is best seen on oblique radiograph
  • apophyseal irregularity

Usually not considered essential for the diagnosis. But if performed may show:

  • T2/STIR: high signal intensity around base of 5th metatarsal due to bone marrow edema 6

History and etymology

First described by H Iselin, a German physician in 1912 4.

Differential diagnosis

On imaging consider:

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