Island sign
Updates to Article Attributes
The Island sign is a radiological sign on non-contrast CT head. It is used as a marker to predict haematoma expansion and prognosis in patients with intracerebral haemorrhage 1. It is posited that the small islands of haematomas represent multiple sources of haemorrhage from injury to adjacent arterioles.
The Island sign is defined as either:
- ≥3 small discrete haematomas that are not connected to the primary haematoma; or
- ≥4 small haematomas that may branch off from the primary haematoma should resemble bubbles or sprouts rather than of lobulated appearance 2
In predicting haematoma expansion, one single-centre retrospective study demonstrated the Island sign had a specificity of 98.2%, sensitivity of 44.7%, positive predictive value of 92.7%, and a negative predictive value of 77.7% 1. Furthermore, the same study demonstrated that the presence of the Island sign was an independent predictor of poor outcomes in patients with intracerebral haemorrhage 1.
-<p>The <strong>Island sign</strong> is a radiological sign on non-contrast CT head. It is used as a marker to predict haematoma expansion and prognosis in patients with intracerebral haemorrhage <sup>1</sup>. It is posited that the small islands of haematomas represent multiple sources of haemorrhage from injury to adjacent arterioles. </p><p> </p><p>The Island sign is defined as either:</p><ul>- +<p>The <strong>Island sign</strong> is a radiological sign on non-contrast CT head. It is used as a marker to predict haematoma expansion and prognosis in patients with <a title="Intracerebral haemorrhage" href="/articles/intracerebral-haemorrhage">intracerebral haemorrhage</a> <sup>1</sup>. It is posited that the small islands of haematomas represent multiple sources of haemorrhage from injury to adjacent arterioles. </p><p> </p><p>The Island sign is defined as either:</p><ul>
References changed:
- 1. Li Q, Liu Q, Yang W et al. Island Sign: An Imaging Predictor for Early Hematoma Expansion and Poor Outcome in Patients With Intracerebral Hemorrhage. Stroke. 2017;48(11):3019-25. <a href="https://doi.org/10.1161/STROKEAHA.117.017985">doi:10.1161/STROKEAHA.117.017985</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/29018128">Pubmed</a>
- 2. Morotti A, Boulouis G, Dowlatshahi D et al. Standards for Detecting, Interpreting, and Reporting Noncontrast Computed Tomographic Markers of Intracerebral Hemorrhage Expansion. Ann Neurol. 2019;86(4):480-92. <a href="https://doi.org/10.1002/ana.25563">doi:10.1002/ana.25563</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/31364773">Pubmed</a>
Sections changed:
- Signs
Systems changed:
- Central Nervous System