Isolated cleft palate

An isolated cleft palate is a type of facial cleft. This is a much rarer occurrence than a cleft lip +/- palate and is thought to represent a different pathological entity.

The estimated incidence is at ~1 per 2000-2500 pregnancies 4-5. There may be a slight female predilection 4

The cleft can involve either the soft or hard palate and may extend as far as the nasopalatine foramen but there is no accompanying cleft lip.

There can be many assoaicted anomalies including:

  • Lamotrigine exposure during pregnancy: possible 6

An isolated cleft palate only rarely identified prenatally. An "absent equals sign" has been proposed as a novel marker where a normal uvula could be visualized with a typical echo pattern (the 'equals sign') in normal cases 7.

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Article information

rID: 14889
Tag: cases
Synonyms or Alternate Spellings:
  • Cleft palate : isolated
  • Cleft palate without cleft lip

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