ISSVA classification of vascular anomalies

The ISSVA classification of vascular anomalies is based on the initial classification published by Mulliken and Glowacki in 1982, and encompasses all vascular malformations and tumours in a framework of internationally consistent nomenclature. The classification was revised in 2014.

It is probably one of the two most widely used classification systems, the other being the Hamburg classification system of vascular malformations


The main organisational principle behind this classification is dividing vascular lesions into:

  • vascular tumours (neoplastic)
    • benign
    • locally aggressive or borderline
    • malignant
  • vascular malformations (non-neoplastic)
    • simple
    • combined
    • those of major named vessels
    • those associated with other anomalies
  • provisionally unclassified vascular anomalies
Vascular tumours
Vascular malformations
Provisionally unclassified vascular anomalies
  • verrucous haemangioma
  • angiokeratoma
  • multifocal lymphangioendotheliomatosis with thrombocytopenia/cutaneovisceral angiomatosis with thrombocytopenia
  • Kaposiform lymphangiomatosis
  • PTEN hamartoma of soft tissue / "angiomatosis" of soft tissue (PTEN)
Vascular tumours and malformations
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Article information

rID: 30963
System: Vascular
Tag: stub, cases, refs
Synonyms or Alternate Spellings:
  • ISSVA vascular anomaly classification

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