Ivy sign (brain)

Last revised by Rohit Sharma on 20 Feb 2024

The ivy sign refers to the MRI brain appearance of patients with moyamoya disease or moyamoya syndrome. Prominent leptomeningeal collaterals result in high signal on FLAIR due to slow flow and vivid contrast enhancement on post-contrast T1 1-3. The sign may be more reliably seen on post-contrast T1 than FLAIR 3. The appearance is reminiscent of the brain having been covered with ivy.

Differential diagnosis

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